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stromectol for sale online The meaning of the endpoints in the clinical trials described here go as follows complete response CR disappearance of all clinical evidences of disease or all target lesions; partial response PR, at least 30 reduction in size of the target lesions; stable disease SD, a 30 reduction or less than 25 increase in the size of all detectable disease; objective response rate ORR refers to the percentage of patients with partial or complete response to therapy tumor reduction; effects refers to those effects that are attributable directly to the drug and not the natural history of the disease; progression free survival PFS means the time between treatment assignments and disease progression or death, not affected by crossover or subsequent therapies and generally based on objective and quantitative assessment; events free survival EFS time from treatment assignments to disease progression, death, or discontinuation of treatment for any reason e